Qo or QO may refer to:

Aeromexpress (IATA airline designator QO) Origin Pacific Airways (IATA airline designator QO) QO, a line of electrical circuit breakers made by Square D Qoheleth, Ecclesiastes, a book of the Hebrew Bible quaestiō, Latin for "question", a possible origin of the question mark Quickoffice, a software package , the region subtag used in the Unicode Common Locale Data Repository for Outlying Oceania