Against the Grain may refer to:
Film, television and radio Against the Grain: More Meat Than Wheat, a 1981 Australian film Against the Grain (TV series), a 1993 American drama series Against the Grain, a radio program produced by the Pacifica Foundation
Literature Against the Grain (novel) or À rebours, an 1884 novel by Joris-Karl Huysmans Against the Grain: A Deep History of the Earliest States, a 2017 book by James C. Scott Against the Grain: An Autobiography, a 1990 book by Boris Yeltsin Against the Grain: How Agriculture Has Hijacked Civilization, a 2004 book by Richard Manning Against the Grain: Mad Artist Wallace Wood, a 2003 book edited by Bhob Stewart Against the Grain, a periodical for librarians published by the Charleston Conference
Music Against the Grain Theatre, an opera company in Toronto, Ontario, Canada
Albums Against the Grain (Acoustic Alchemy album) or the title song, 1994 Against the Grain (Bad Religion album) or the title song, 1990 Against the Grain (Kurupt album), 2005 Against the Grain (Phoebe Snow album), 1978 Against the Grain (Redgum album), 2004 Against the Grain (Rory Gallagher album), 1975 Against the Grain (The Veer Union album), 2009 Against da Grain, by YoungBloodZ, 1999 Against the Grain, by Snakefinger, 1983
Songs "Against the Grain", by Akon from Freedom, 2008 "Against the Grain", by Garth Brooks from Ropin' the Wind, 1991
Other uses Against the grain, a direction of woodworking in relation to a piece's wood grain Against the Grain Brewery, a brewery in Kentucky