Scherzer is a surname. Notable people with the surname include:
Ernst Scherzer, German writer, pseudonym of Christian August Gottlob Eberhard (1769–1845) Julius Scherzer (born 1928), Romanian chemist Karl von Scherzer (1821–1903), Austrian explorer Max Scherzer (born 1984), American baseball pitcher Otto Scherzer (1909–1982), German theoretical physicist Steffi Scherzer (born 1957), German ballet dancer William Donald Scherzer (1858–1893), American engineer, "Scherzer" system of Bascule bridges
See also Alex Sherzer (1971–2022), American chess grandmaster and medical doctor Joel Sherzer (1942–2022), American anthropological linguist and academic