William Wiley may refer to:
William Wiley (editor) (fl. 1930s), American civil rights activist and newspaper editor William H. Wiley (1842–1945), U.S. Representative from New Jersey William T. Wiley (1937–2021), American contemporary artist Bill Wiley (William D. Wiley, born 1971), American politician , a United States Navy destroyer, named after sailor William Wiley
See also William Wyllie (disambiguation)