Issy-l'Évêque () is a commune in the Saône-et-Loire department in the region of Bourgogne-Franche-Comté in eastern France.
Personalities Irène Némirovsky (1903–1942), the Ukrainian-Jewish-French novelist lived there during part of World War II; she was arrested in Issy-l'Évêque on 13 July 1942.
See also Communes of the Saône-et-Loire department
References