MSD may refer to:

People Mahendra Singh Dhoni or MSD (born 1981), Indian cricketer

Companies Merck Sharp and Dohme (MSD), an international name of Merck & Co., the U.S. and Canada pharmaceutical company formerly related to German Merck KGaA MSD Capital, a private investment firm owned by personal computer entrepreneur Michael Dell MSD Ignition, a company that specializes in automotive-ignition components; MSD stands for "multiple spark discharge" Motor Sports Developments, an automotive-engineering company based in Milton Keynes, United Kingdom; see X25XE

Computers Mass storage device, like a USB key Memory Stick Duo, a type of solid digital data storage device Microsoft Diagnostics, a computer diagnostic program shipped with various versions of DOS and Microsoft Windows operating systems Modem Sharing Device MSD Super Disk, a floppy-disk drive for Commodore 8-bit systems miniSD/microSD

Organizations Schools and school districts Marjory Stoneman Douglas High School, Florida, United States Stoneman Douglas High School shooting Marshall School District in Marshall, Arkansas, United States Maryland School for the Deaf, United States Milford School District, a school district in Milford, Delaware, United States Missouri School for the Deaf Moscow School District in Moscow, Idaho, United States

Other organizations Meclîsa Sûriya Demokratîk or Syrian Democratic Council, the political wing of the Syrian Democratic Forces in Syria Metro de Santo Domingo, a rapid-transit system in Santo Domingo, the capital of the Dominican Republic Ministry of Social Development (New Zealand) Mission Science Division, a group of scientists, research fellows and young graduates working at the European Space Agency Mladí sociální demokraté or Young Social Democrats (Czech Republic), a social democratic youth organization in the Czech Republic Mladí sociálni demokrati or Young Social Democrats (Slovakia), a social democratic youth organization in Slovakia Mobile Security Deployments, the U.S. Diplomatic Security Service's tactical unit MSD (Межправительственный совет дорожников) or Intergovernmental Council of Roads, the road authority organisation of the Commonwealth of Independent States

Science and medicine Macromolecular Structure Database, one of the services provided by the European Bioinformatics Institute Major hypersomnolence disorder Marine sanitation device, used in the Regulation of ship pollution in the United States#Marine sanitation devices Mars solar date Mass spectrometric detector, a type of chromatography detector Mean squared displacement, a statistical measure of random motion Mean signed deviation, a measure of statistical deviation Multiple sulfatase deficiency, a very rare form of metachromatic leukodystrophy Musculoskeletal disorders

Other uses Magnetic switchable device, a passive magnetic mount that can be activated or deactivated Master Scuba Diver, a certification level in recreational scuba diving Master of Science in Dentistry, a dental degree Master of Sport Directorship, at Manchester Metropolitan University Mean Shortest Distance, in the context of the PGP Web of trust Minimum string distance, the number of insertions, deletions, or substitutions to transform one string into another in minimum string distance error rate Station code for Moorside railway station, England Moscow Summer Time Most significant digit Postal code for Msida, Malta Masjid railway station (station code: MSD), Mumbai, India