Manuel Soto may refer to:
Manuel Ángel Núñez Soto (born 1951), Mexican politician Manuel Esteban Soto (born 1994), Colombian athlete Manoel Soto (1944–2019), Spanish politician, also spelled as Manuel Soto Manuel Soto (wrestler), (born 1946), Puerto Rican professional wrestler, known for his time in WWWF/WWF.