Thomé and Thome are French or German variants of the name Thomas which now appears as a surname and in placenames.

Places Saint-Thomé, commune in the Ardèche department, France São Thomé das Letras, city in Minas Gerais state, Brazil San Thome Basilica, Roman Catholic cathedral in Chennai (Madras), India Thome, ancient name of Ithome (Thessaly), in Greece

People Thome Rodrigo (c. mid-1500s), Sri Lankan Sinhala Karava noble, signatory of the Convention of Malvana between the Kingdom of Portugal and the Kingdom of Kotte André Thome (1879-1916), French politician. Delfina Thome (born 1996), Argentine field hockey player Diane Thome (1942–2025), American composer Emerson Thome (born 1972), Brazilian former football player Francis Thomé (1850–1909), French pianist and composer Jim Thome (born 1970), Major League Baseball hitter Joel Thome, American conductor John M. Thome (1843–1908), American-Argentine astronomer Johannes Thome, European psychiatrist and scientist Otto Wilhelm Thomé (1840–1925), German botanist and botanical artist Rudolf Thome (born 1939), German film director and producer Verner Thomé (1878-1953), Finnish painter Xavier Noiret-Thomé (born 1971), French painter