OPL may stand for:
Computing and technology Open Programming Language Optical path length Optimization Programming Language, a modelling language designed for the CPLEX Optimization software FM Operator Type-L, a series of sound chips made by Yamaha: YM3526 (OPL) YM3812 (OPL2) YMF262 (OPL3) YMF278 (OPL4)
Libraries Oakville Public Library, in Oakville, Ontario Oshawa Public Library, in Oshawa, Ontario Ottawa Public Library, in Ottawa, Ontario One-person library Omaha Public Library, in Omaha, Nebraska Orem Public Library, in Orem, Utah
Sports Oceanic Pro League, a former professional League of Legends league in Oceania Oman Professional League, an association football league in Oman Ontario Premier League, a Canadian association football league
Other Luxembourg Philharmonic Orchestra, abbreviated to OPL On Patrol: Live, an American docuseries that uses the abbreviation OPL Optique & Précision de Levallois (1911-1964), a former French optical company Open Publication License, license predating Creative Commons licenses Operating lease Organisation du Peuple en Lutte ("Struggling People's Organization"), a Haitian political party