Polignac may refer to:
Polignac family, a French noble family, including a list of its members Duke of Polignac, a title created in 1780 for the Polignac family Polignac (card game), a French card game for four players
Places Polignac, Charente-Maritime, a municipality in the Charente-Maritime department, France Polignac, Haute-Loire, a municipality in the Haute Loire department, France