The Molise regional election of 2001 took place on 11 November 2001. It was an early election as the 2000 regional election was invalidated due to irregularities in the vote.

The election consisted in a re-proposition of the 2000 race, but this time Michele Iorio (Forza Italia) defeated incumbent Giovanni Di Stasi (Democrats of the Left) by a landslide.

Results Candidates & parties votes votes (%) seatsreg. list seatsprov. lists Michele Iorio115,71458.21315 Forza Italia43,57322.93→6 Christian Democratic Centre–United Christian Democrats25,81213.58→3 European Democracy24,28112.78→3 National Alliance20,30210.68→3 Tricolour Flame1,4690.77→0 Socialists–The Liberals-Sgarbi1,0680.57→0 Giovanni Di Stasi83,08941.79111 Democracy is Freedom – The Daisy 27,71714.59→4 Democrats of the Left22,83812.02→4 Italy of Values8,8524.66→1 Communist Refoundation Party6,6403.49→1 Federation of the Greens–Party of Italian Communists5,3132.80→1 Italian Democratic Socialists2,1541,13→1 Total198,803100.00426 Source: Ministry of the Interior