Heebie-jeebies is a phrase, widely attributed to Billy DeBeck, meaning a feeling of anxiety, apprehension, depression or illness.

Heebie-jeebies or heebie jeebies may also refer to:

"Heebie Jeebies" (composition), a 1926 single by Louis Armstrong and his Hot Five "Heeby-Jeebies", a 1956 single by Little Richard "Heebiejeebies", a song on the album Good for You by Aminé featuring Kehlani The Heebee-jeebees, an a capella band from Canada The Hee Bee Gee Bees, a comedy parody of the Bee Gees Heebee Jeebees, a 1927 lost comedy film Heebie Jeebies (film), a 2013 science fiction horror film