APL is an abbreviation, acronym, or initialism that may refer to:
Science and technology 132524 APL, an asteroid Abductor pollicis longus muscle, in the human hand Acute promyelocytic leukemia, a subtype of acute myelogenous leukemia Applied Physics Letters, a physics journal Applied Physics Laboratory, at Johns Hopkins University Applied Physics Laboratory at the University of Washington
Computing .apl, the file extension of the Monkey's Audio metadata file AMD Performance Library, renamed Framewave, a computer compiler library; see Address Prefix List, a DNS record type Advanced Physical Layer, an extension of Ethernet 10BASE-T1L for field devices APL (codepage), the character set for programming in APL
Computer languages APL (programming language), an array-based programming language Address programming language, an early high-level programming language developed in the Soviet Union Associative Programming Language, a database query language Alexa Presentation Language, a language for developing Amazon Alexa skills
Legal agreements for software and data Adaptive Public License, an Open Source license from the University of Victoria, Canada AROS Public License, a license of AROS Research Operating System Arphic Public License, a free font license
Military and politics A US Navy hull classification symbol: Barracks craft (APL) Aden Protectorate Levies, a militia force for local defense of the Aden Protectorate American Protective League, a World War I-era pro-war organization Irish Anti-Partition League, a Northern Ireland political organisation
Transportation Nampula Airport (IATA airport code: APL), in Mozambique American President Lines, a container transportation and shipping company Advanced Production and Loading, a Norwegian marine engineering company formed in 1993 APL Logistics, a Japan-based freight forwarding and transportation company
Sport
American Patriot League, a proposed American football spring league American Premiere League, a Twenty20 cricket league in the US Afghanistan Premier League, a defunct Afghan Twenty20 cricket league Afghanistan Premier League (2026), an Afghan Twenty20 cricket league
Association football / soccer Australian Professional Leagues, an Australian governing body Afghan Premier League, a men's league in Afghanistan Alberta Premier League, a Canadian league Abkhazian Premier League, the top-level league of Abkhazia Armenian Premier League, the top-level league of Armenia Azerbaijan Premier League, the top-level league of Azerbaijan
Other uses apl.de.ap (born 1974), pseudonym of Allan Pineda Lindo, Filipino–American musician Association of Pension Lawyers, UK Athletic Propulsion Labs, an American clothing company formed in 2009 Aurora Public Library (disambiguation)
See also APL Pipers (formerly the Delhi SG Pipers), an Indian field hockey team A. P. L. Bazin (Antoine-Pierre-Louis; 1799–1863), French sinologist APL Materials, a scientific journal published by the American Institute of Physics APL Photonics, a scientific journal published by the American Institute of Physics AAPL (disambiguation) APPL: Area Police/Private Security Liaison APLL (disambiguation)