HMC may stand for:
Education Harvey Mudd College, Claremont, California, US Headmasters' and Headmistresses' Conference, UK organisation of independent fee-charging schools Harvard Model Congress, congressional simulation conference Harris Manchester College, Oxford, a constituent college of the University of Oxford
Companies Hamad Medical Corporation, Qatar Harvard Management Company, manages Harvard University endowment Heerema Marine Contractors, The Netherlands Hero Motors Company, of India Holyoke Machine Company, defunct, United States Honda Motor Company, of Japan, NYSE symbol Hornady Manufacturing Company (cartridge headstamp) Hyundai Motor Company, of Republic Of Korea
Transport Hamamatsuchō Station, JR East station code Hampton Court railway station, the terminus of the Hampton Court Branch Line in Surrey, SW of London
Other Chief Hospital corpsman, a United States Navy rate Half Mini Card, a physical specification of the PCI Express Mini Card Hardware Management Console, a computer technology provided by IBM His/Her Majesty's Cutter, UK Customs ship prefix since 2005 Herzliya Medical Center, Herzliya, Israel Holocaust Memorial Center Holyoke Medical Center Hybrid Memory Cube, a computer memory (RAM) technology Royal Commission on Historical Manuscripts, or Historical Manuscripts Commission Hamiltonian Monte Carlo