Rafael Nadal defeated John Isner in the final, 7–6(10–8), 7–6(7–3) to win the men's singles tennis title at the 2013 Cincinnati Open. It was his record-extending 26th Masters title. Nadal was the second man (after Novak Djokovic) to win four consecutive Masters 1000 events.
Roger Federer was the defending champion, but lost in the quarterfinals to Nadal.
Seeds The top eight seeds receive a bye into the second round.
Draw
Finals
Top half
Section 1
Section 2
Bottom half
Section 3
Section 4
Qualifying
Seeds
Qualifiers
Qualifying draw
First qualifier
Second qualifier
Third qualifier
Fourth qualifier
Fifth qualifier
Sixth qualifier
Seventh qualifier
References Main Draw Qualifying Draw