Spargo is a surname. Notable people with the surname include:
Anna Spargo-Ryan, Australian author and scriptwriter Anthony Spargo (born 1980), British actor and playwright Bob Spargo Sr. (1913–1994), Australian rules footballer Bob Spargo (born 1939), Australian rules footballer Charlie Spargo (born 1999), Australian rules footballer John Spargo (1876–1966), British political writer and socialist John Spargo (water polo) (born 1931), American water polo player John Warren Spargo, American electronic engineer Marty Spargo, Australian entrepreneur Mary Spargo (1904–1991), American newspaper journalist Paul Spargo (born 1966), Australian rules footballer Ricky Spargo (born 1947), Australian rules footballer R. Clifton Spargo (born 1965), American novelist Stephen Spargo (1903–1972), English footballer Thomas J. Spargo, American attorney and judge Tony Spargo, professional name of Tony Sbarbaro (1897–1969), American jazz drummer
Fictional characters Harry Spargo and his wife Beryl, characters in the television series Upstairs Downstairs
Other Spargo (band), a Dutch disco-funk-band
See also Lower Spargo and Upper Spargo, hamlets in Cornwall, county in South West England