Santorio is an Italian surname that may refer to Francesco Antonio Santorio (died 1589), Roman Catholic prelate Giovanni Antonio Santorio (died 1628), Roman Catholic prelate Giovanni Battista Santorio (died 1592), Roman Catholic prelate Giulio Antonio Santorio (1532–1602), Cardinal of the Roman Catholic Church Santorio Santorio (1561–1636), Italian physiologist and physician
See also Santori Santoro