Napolioni is both an Italian surname and a given name. Notable people with the name include:
Antonio Napolioni (born 1957), Italian Roman Catholic bishop Marco Napolioni (born 1975), Italian footballer Napolioni Bolaca (born 1996), Fijian rugby union player Napolioni Nalaga (born 1986), Fijian rugby union player Napolioni Qasevakatini (born 1993), Fijian footballer