David Bruce may refer to:
Entertainment David Bruce (actor) (1914–1976), American film actor David Bruce (composer) (born 1970), British composer David Bruce (bridge) (1900–1965), American contract bridge player in the 1930s
Science David Bruce (physician) ( 1660s), Scottish physician David Bruce (microbiologist) (1855–1931), Scottish pathologist and microbiologist David Bruce (naturalist) (1833–1903), Scottish-American natural history collector
Other David II of Scotland (1324–1371), David Bruce, King of Scots, son of King Robert the Bruce David Bruce (captain) (1816–1903), British master mariner David Bruce (minister) (1824–1911), Presbyterian minister, journalist David K. E. Bruce (1898–1977), American diplomat David Bruce (brewer) (born 1948), British entrepreneur, founder of the Firkin Brewery pub chain David Bruce (ice hockey) (born 1964), Canadian National Hockey League player David Bruce (inventor) (1802–1892), American industrialist and inventor
See also Bruce LM–5000 Pairs, an American contract bridge competition David Bruce Winery, an American winery David Bryce (1803–1876), Scottish architect