Danford is both a surname and a given name. Notable people with the name include:

Surname Ben Danford (born 2006), Canadian ice hockey player Dave Danford (born 1984), British percussionist Harry Danford (born c. 1939), Politician in Ontario Lorenzo Danford (1829–1899), U.S. Representative from Ohio Ryan Danford (born 1985), Professional American Halo player

Given name Arnold Danford Patrick Heeney (1902–1970), Canadian lawyer, diplomat and civil servant Danford Balch (1811–1859), Oregon pioneer Danford N. Barney (1808–1874), American expressman Danford B. Greene (1928–2015), American film and television editor Samuel Danford Nicholson (1859–1923), United States Senator

See also Danford iris (Iris danfordiae), bulbous perennial, in the species in the genus Iris Samuel Danford Farm, historic complex of buildings in northeastern Noble County, Ohio, United States