Diederichs is a German surname. Notable people with the surname include:
Eugen Diederichs (1867–1930), German publisher Georg Diederichs (1900–1983), German politician Klaus Diederichs, English banker Nico Diederichs (1903–1978), South African politician Otto von Diederichs (1843–1918), Imperial German Navy admiral
See also Helene Voigt-Diederichs (1875–1961), German writer Diederich