Jefferson House may refer to:

in Sri Lanka Jefferson House, Columbo

in the United States Monticello, Charlottesville, Virginia, home of president Thomas Jefferson Joe Jefferson Clubhouse, Saddle River, New Jersey, listed on the National Register of Historic Places (NRHP) Joseph Jefferson House, Jefferson Island, Louisiana, NRHP-listed W. E. Jefferson House, Boise, Idaho, NRHP-listed in Ada County John P. Jefferson House, Warren, Pennsylvania, NRHP-listed

See also Jefferson Hall (disambiguation) Jefferson School (disambiguation)