De Caluwé, or Decaluwé, is a surname. Notable people with the name include:

People Carl Decaluwé (born 1960), Belgian politician Edgard De Caluwé (1913–1985), Belgian cyclist Ingrid de Caluwé (1967-), Dutch politician Jackie De Caluwé (1934–2021), Belgian footballer Katleen De Caluwé (1976-), Belgian sprinter Robby De Caluwé (1975-), Belgian politician Sylvie De Caluwé (1986-), Belgian model

See also Tom Caluwé (1978-), Belgian footballer