Mules are the hybrid animals born to a male donkey and female horse.

Mules may also refer to:

Sports teams Mules, the sports teams of Leilehua High School, Wahiawa, Hawaii Mules, the sports teams of Muleshoe High School, Muleshoe, Texas Mules, the sports teams of Muhlenberg College, Allentown, Pennsylvania Central Missouri Mules and Jennies, the sports teams of the University of Central Missouri Colby Mules, the sports teams of Colby College, in Waterville, Maine New Britain Mules, a 1930s American Basketball League team Newark Bears (basketball), an American Basketball League team renamed the Newark Mules for the 1934 season; merged with the New Britain Jackaways to form the New Britain Mules in the second half of the season St. Louis Mules, a member of the American Soccer League in the 1972 season

Other uses Mules (train), passenger trains operated by Amtrak running between St. Louis and Kansas City, Missouri as part of the Missouri Service train network Mules (surname)

See also Mule (disambiguation) Mule (surname)