Flinders Lofty Block is an interim Australian bioregion located in South Australia. It has an area of , which includes the Mount Lofty Ranges and Flinders Ranges.

Subregions Flinders Lofty Block consists of six subregions: Mount Lofty Ranges (FLB01) –  Broughton (FLB02) –  Olary Spur (FLB03) –  Southern Flinders (FLB04) –  Northern Flinders (FLB05) –  Central Flinders (FLB06) – 

The Mount Lofty Ranges and Broughton subregions are part of the Mount Lofty woodlands ecoregion. The other subregions are part of the Tirari–Sturt stony desert ecoregion.

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