Sansonetti is an Italian surname. Notable people with the surname include:
Étienne Sansonetti (1935–2018), French football player Federico Sansonetti (born 1986), Uruguayan tennis player Luigi Sansonetti (1888–1959), Italian admiral Philippe Sansonetti (born 1949), French microbiologist Remo Sansonetti (born 1946), Australian cyclist Sal Sansonetti (born 1946), Australian cyclist Sarah Sansonetti (born 2001), Australian football player Tom Sansonetti (born 1949), American attorney and government official from Wyoming Ugo Sansonetti (1919–2019), Italian writer and athlete