Estifanos is a name. Notable people with the name include:

Estifanos Seyoum (born 1947), Eritrean politician Abba Estifanos of Gwendagwende, Ethiopian monk Dawit Estifanos (born 1988), Ethiopian footballer Mereb Estifanos (born 1983), Eritrean actress Tewelde Estifanos (born 1981), Eritrean long-distance runner