Mbakwe is a surname of Igbo origin that means "let the nation agree”. This is similar to other kwe-suffix names (e.g., Chikwe, Ibekwe, Igbokwe and Ndukwe). Notable people with this surname include:

Jaylen Mbakwe (born 2005), American college football wide receiver Sam Mbakwe (1929–2004), Nigerian politician and first democratic governor of Imo State Trevor Mbakwe (born 1989), American professional basketball coach and former player

See also Sam Mbakwe Airport, airport in Ngor Okpala Local Government Area, Imo State, Nigeria. Named after Sam Mbakwe

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