Pootoogook () is an Inuit surname. Notable people with this surname include: Annie Pootoogook (1969–2016), Canadian artist Eegyvudluk Pootoogook (1931–2000), Canadian sculptor Elijah Pudlat Pootoogook (born 1943), Canadian artist Kananginak Pootoogook (1935–2010), Canadian sculptor Napachie Pootoogook (1938–2002), Canadian artist Sharni Pootoogook (1922–2003), Canadian printmaker