Fathead may refer to:
Company Fathead (brand), a graphics company specializing in sports decorations and custom wall graphics
Fish Fathead carp Fathead minnow Fathead sculpin Cubiceps Semicossyphus pulcher of the family Labridae Psychrolutes microporos of the family Psychrolutidae
Music David "Fathead" Newman (1933-2009), American jazz and R&B saxophonist Fathead (album), Newman's debut release Fathead (musician) (c. 1960–1988), Jamaican dance hall deejay Fathead (band), Canadian blues band
Other uses Fat Head, a documentary criticizing Super Size Me and seeking to refute the lipid hypothesis The Fatheads, a show within a show on Rocko's Modern Life