SP1 and variants may refer to:
Bowlus SP-1 Paper Wing, glider SP-1 switch, a late 1960s telecommunications switch by Northern Electric Sp1 transcription factor, a human protein Dallara SP1, a race car Savoia-Pomilio SP.1, a reconnaissance and bomber aircraft built in Italy during the First World War USS Arawan II (SP-1), a motor yacht that served in the United States Navy as a patrol vessel from 1917 to 1918 Vektor SP1/SP2, a pistol SP-01, a variant of the CZ 75 pistol Shapley 1, an annular planetary nebula in the constellation of Norma Service pack 1, a collection of computer program patches and alterations Surface Pro, a laplet by Microsoft Skulduggery Pleasant (novel), a young adult fiction novel by Derek Landy a model of steam toy made by British manufacturer Mamod a sink in the Sima Pumacocha, a cave in Peru