PLC or plc may refer to:
Public limited company, a type of public company
Education Platoon Leaders Class, of the US Marine Corps Officer Candidates School Post Leaving Certificate, a qualification in Ireland Presbyterian Ladies' College (disambiguation), several schools in Australia Professional learning community, for collaborative learning
Medicine Perlecan, a protein in humans Peptide loading complex, an intracellular membrane protein matrix Peter Lougheed Centre, a hospital in Calgary, Alberta, Canada Phospholipase C, a class of membrane-associated enzymes Pityriasis lichenoides chronica, a skin condition Posterolateral corner, a region of the human knee
Politics Colombian Liberal Party () Conservative Party (Spain) () Constitutionalist Liberal Party (), in Nicaragua Liberal Party of Canada () Palestinian Legislative Council, of the Palestinian Authority Pennsylvania Leadership Conference, in the US Presidential Leadership Council, in Yemen Provisional Legislative Council, in Hong Kong 1997–1998
Technology Packet loss concealment, in VoIP communications Planar lightwave circuit splitter, a type of fiber-optic splitter Portevin–Le Chatelier effect, jerky flow under plastic deformation Power-line communication, or power-line carrier Product lifecycle, from inception to manufacture Programmable logic controller, an industrial digital computer
Other uses Phi Life Cypher, a British hip hop group Pine Lake Camp, one of the Salvation Army camps in Canada Polish–Lithuanian Commonwealth Portland Lesbian Choir, in Oregon, US Prism Leisure Corporation, a former British company UAE Pro League Committee, a football organising committee
See also PL/C, a programming language